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Allele : Ccnd1<tm1Phin> cyclin D1; targeted mutation 1, Philip W Hinds

Primary Identifier  MGI:3614415 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Ccnd1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a point mutation into exon 2 that resulted in a K112E substitution. Crossing with mice expressing cre recombinase removed a floxed neo cassette. Normal levels of protein were found in mutant heart, lung, spleen, liver and kidney samples. A slower-migrating protein was detected in mutant tissues.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • cyclin D1<KE>,
  • cyclin D1<KE>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories