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Transgene : Tg(CD2-Tgfbr2)1Grs transgene insertion 1, Ronald E Gress
Primary Identifier  MGI:3614437 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Transgenic mice develop a severe lymphoproliferative disorder involving the spleen, lymph nodes and lymphocyte infiltration of other organs that progresses to leukemia/lymphoma, when mice become lethargic and lose weight. The rate of disease progression is correlated with transgene copy number. [provided by MGI curators]
  • synonyms:
  • DNRII,
  • transgene insertion 1, Ronald E Gress,
  • Tg(CD2-Tgfbr2)1Grs,
  • dominant-negative TGF-beta type II receptor transgene
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