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Allele : Srms<tm1Sia> src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; targeted mutation 1, Shinichi Aizawa

Primary Identifier  MGI:3616183 Allele Type  Targeted
Attribute String  Null/knockout Gene  Srms
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ gene and neomycin resistance cassette was inserted in to the exon encoding the fourth kinase domain. The lacZ gene was fused in-frame to the endogenous gene. Northern blot analysis demonstrated that no detectable transcript was expressed from this allele, and histochemical staining failed to detect beta-galactosidase in multiple tissues tested.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

5 Publication categories