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Allele : Rb1<tm1Dwg> RB transcriptional corepressor 1; targeted mutation 1, David W Goodrich
Primary Identifier  MGI:3617652 Allele Type  Targeted
Attribute String  Hypomorph, Modified isoform(s) Gene  Rb1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Arginine codon 654 (CGA) exon 20 was changed to tryptophan (TGG) (p.R654W). The loxP site flanked neomycin resistance gene cassette that was inserted into intron 19 was removed via Cre-mediated recombination. Western blot demonstrated protein levels were approximately the same in mutants and wild-type.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Rb1<654>,
  • Rb R654W,
  • Rb1<654>,
  • Rb R654W
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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