| Primary Identifier | MGI:3620550 | Allele Type | Targeted |
| Attribute String | Not Specified | Gene | Cdkn1b |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to insert an S10A mutation into exon 1. A neomycin resistance gene that was included in the vector was subsequently removed via cre-mediated excision. Protein was reduced in mutant brain, thymus, spleen and testis compared to wild-type. Protein levels in liver, heart, lung and skeletal muscle were not affected by the mutation. |
