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Allele : Sufu<tm1Rto> SUFU negative regulator of hedgehog signaling; targeted mutation 1, Rune Toftgard

Primary Identifier  MGI:3619046 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sufu
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A vector was designed to replace part of the promoter, 5' UTR and first exon, including both transcription and translation start sites, with a neomycin resistance cassette. Northern blot did not detect transcript in mutants and Western blot analysis failed to detect protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Sufu<->,
  • Sufu<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

12 Publication categories