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Allele : Hif1a<tm2Mcs> hypoxia inducible factor 1, alpha subunit; targeted mutation 2, M Celeste Simon

Primary Identifier	MGI:3619142	Allele Type	Targeted
Attribute String	Inserted expressed sequence, No functional change	Gene	Hif1a
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A cDNA encoding c-Myc epitope tagged Hif1a was fused to the SV40 polyA sequence and was inserted into exon 1 of the locus. This allele was created as a control for MGI:3613538.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Hif-1alpha KI,
Hif-1alpha KI

earliestPublication:
Covello KL, et al. (2006) HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 20(5):557-70

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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