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Allele : Ppp1r1b<tm1Pggd> protein phosphatase 1, regulatory inhibitor subunit 1B; targeted mutation 1, Paul Greengard
Primary Identifier  MGI:3620646 Allele Type  Targeted
Gene  Ppp1r1b Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Threonine 34 was replaced with an alanine to prevent phosphorylation. Immunoblot confirmed presence of the mutation. A neomycin resistance cassette included in the targeting construct was deleted via cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • DARPP-32 T34A,
  • A34T,
  • T34A-DARPP-32,
  • Thr<34>-DARPP-32,
  • T34A-DARPP-32,
  • DARPP-32 T34A,
  • A34T,
  • Thr<34>-DARPP-32
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

19 Publication categories

Trail: Allele




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