Primary Identifier | MGI:3618929 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(CAG-cre/Esr1*)86Lbgn |
Strain of Origin | (C57BL/6 x DBA)F1 | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | This transgene expresses cre recombinase as a fusion protein with two copies of a tamoxifen-responsive estrogen receptor under the control of the CMV enhancer/ chicken beta-actin promoter. Expression was detected in a patchy pattern, with the highest levels of expression in skeletal and heart muscle tissue. In kidneys, cre is expressed in the nucleus of podocytes. |