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Allele : Kcnab1<tm1Mes> potassium voltage-gated channel, shaker-related subfamily, beta member 1; targeted mutation 1, Albee Messing

Primary Identifier	MGI:3619233	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Kcnab1
Transmission	Germline	Strain of Origin	129S7/SvEvBrd-Hprt1<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 1a was replaced with a neomycin resistance cassette. The most abundant brain isoform was thus deleted while the primary heart isoform continued to be expressed.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

synonyms:
KvBeta1.1 null,
KvBeta1.1 null

earliestPublication:
Connor JX, et al. (2005) Genetic modifiers of the Kv beta2-null phenotype in mice. Genes Brain Behav 4(2):77-88

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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