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Allele : Gipc3<ahl5-Black Swiss> GIPC PDZ domain containing family, member 3; age related hearing loss 5-Black Swiss

Primary Identifier  MGI:3622811 Allele Type  QTL
Gene  Gipc3 Inheritance Mode  Recessive
Strain of Origin  Black Swiss Is Recombinase  false
Is Wild Type  false
description  Animals homozygous for Black Swiss-derived alleles at Ahl5 and Ahl6 exhibit significantly increased hearing threshold.
molecularNote  A G to A (G343A) nucleotide substitution in exon 2 of the Gipc3 gene that results in the amino acid substitution of glycine for arginine at position 115 within the PDZ domain (aa107-174). This allele confers increased hearing threshold compared to CAST/EiJ.
  • synonyms:
  • Gipc3<343A>,
  • Gipc3<343A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories