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Allele : Jag1<tm1Jlew> jagged 1; targeted mutation 1, Julian Lewis
Primary Identifier  MGI:3623344 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Jag1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted to flank exons encoding the DSL (Delta-Serrate-Lag2) domain required for binding to Notch. Expression of cre recombinase is expected to knock out gene function by removing exons 4 and 5 (the DSL encoding exons) and causing a frame shift that generates a stop codon after the start of exon 6.
  • mutations:
  • Insertion
  • synonyms:
  • Jag1<flox>,
  • Jag1<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories





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