Primary Identifier | MGI:3622200 | Allele Type | QTL |
Gene | Pgis2 | Inheritance Mode | Dominant |
Strain of Origin | BALB/c | Is Recombinase | false |
Is Wild Type | false |
description | F2 animals homozygous for DBA/2-derived alleles at Pgis1 and homozygous for BALB/c-derived alleles at Pgis2 exhibit the highest spondylitis incidence and severity. |
molecularNote | This allele confers susceptibility to proteoglycan-induced spondylitis compared to DBA/2. |