Primary Identifier | MGI:3623206 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Psen1 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 10, which encodes most of the hydrophilic loop, was removed from the locus via cre-mediated recombination. Western blot detected a truncated C-terminal fragment due to the deletion of the exon. |