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Publication : Expression of Sox genes in tooth development.

First Author  Kawasaki K Year  2015
Journal  Int J Dev Biol Volume  59
Issue  10-12 Pages  471-8
PubMed ID  26864488 Mgi Jnum  J:229536
Mgi Id  MGI:5752417 Doi  10.1387/ijdb.150192ao
Citation  Kawasaki K, et al. (2015) Expression of Sox genes in tooth development. Int J Dev Biol 59(10-12):471-8
abstractText  Members of the Sox gene family play roles in many biological processes including organogenesis. We carried out comparative in situ hybridization analysis of seventeen sox genes (Sox1-14, 17, 18, 21) during murine odontogenesis from the epithelial thickening to the cytodifferentiation stages. Localized expression of five Sox genes (Sox6, 9, 13, 14 and 21) was observed in tooth bud epithelium. Sox13 showed restricted expression in the primary enamel knots. At the early bell stage, three Sox genes (Sox8, 11, 17 and 21) were expressed in pre-ameloblasts, whereas two others (Sox5 and 18) showed expression in odontoblasts. Sox genes thus showed a dynamic spatio-temporal expression during tooth development.
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