Primary Identifier | MGI:3624634 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(KRT5-CDK4)2303Mlrp |
Strain of Origin | FVB | Is Recombinase | false |
Is Wild Type | false |
molecularNote | cDNA encoding the human cyclin-dependent kinase 4 gene was placed into a vector under control of the bovine keratin 5 regulatory sequences and containing the rabbit beta-globin intron 2 and the SV40 3' polyadenylation sequences. Western blots of epidermal tissue showed a 7.5-fold increase in CDK4 protein levels in this line. |