| Primary Identifier | MGI:3623943 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting construct was designed to change the seven C-terminal lysines to arginine (p.K367R, p.K369R, p.K370R, p.K378R, p.K379R, p.K383R, p.K384R). A loxP site flanked neomycin resistance gene cassette was included in the vector, which was electroporated into ES cells carrying a self-excising cre recombinase gene. |
