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Allele : Espl1<tm1.2Tno> extra spindle pole bodies 1, separase; targeted mutation 1.2 Tetsuo Noda

Primary Identifier  MGI:3624003 Allele Type  Targeted
Attribute String  Null/knockout Gene  Espl1
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A 1.4 kb genomic segment including exon 6 was removed via cre mediated recombination. RT-PCR detected reduced amounts of transcript in heterozygotes. Sequencing revealed that the splicing of exons 5-7, which encode a frame shift mutation at codon 452, generated this transcript.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Separase<null>,
  • Separase<null>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories