Primary Identifier | MGI:3624003 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Espl1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 1.4 kb genomic segment including exon 6 was removed via cre mediated recombination. RT-PCR detected reduced amounts of transcript in heterozygotes. Sequencing revealed that the splicing of exons 5-7, which encode a frame shift mutation at codon 452, generated this transcript. |