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Allele : Lmr17<CcS20/Dem> leishmaniasis resistance 17; CcS20/Dem

Primary Identifier  MGI:3625874 Allele Type  QTL
Gene  Lmr17 Inheritance Mode  Other (see notes)
Strain of Origin  CcS20/Dem Is Recombinase  false
Is Wild Type  false
description  Lmr17 exhibits additive inheritance.

Lmr17 interacts with Lmr3 on chromosome 5 to influence serum IFN-gamma levels. F2 animals homozygous for BALB/cHeA-derived alleles at Lrm3 and STS/A-derived alleles at Lrm17 exhibit higher serum IFN-gamma concentrations.

molecularNote  STS/A alleles at this locus were associated with increased levels of TNF alpha in serum. Homozygous BALB/c alleles at Lmr24f and homozygous STS/A alleles at Lmr17 (D9Mit2) increase IFN gmma levels.
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories