Primary Identifier | MGI:3625967 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Yy1 |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1 and the promoter region were flanked with loxP sites by homologous recombination. An FRT-flanked neomycin cassette was inserted downstream of the 3' loxP site. Protein expression in heterozygotes is reduced by about 25% compared to wild-type mice. |