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Allele : Dnmt3b<tm6Enl> DNA methyltransferase 3B; targeted mutation 6, En Li

Primary Identifier  MGI:3628446 Allele Type  Targeted
Attribute String  Humanized sequence, Hypomorph Gene  Dnmt3b
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert an A609T substitution, replicating the A603T mutation found in some human ICF syndrome patients. Cre mediated recombination removed a floxed IRES-betageo from the locus. This allele produced protein at levels similar to those of wild-type mice.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Dnmt3b<T>,
  • Dnmt3b<T>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories