| Primary Identifier | MGI:3628759 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Adam1b |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A vector was designed to replace the 455-residue protein-coding region containing the pro-metalloprotease, disintegrin, and cysteine-rich domains at positions 79-533 with a neomycin resistance gene. Absense of transcript was confirmed in Northern blot of mutant testis. Also, protein extracts from testicular germ cells lacked a 120-kDa protein corresponding to the precursor form of Adam1b protein. |
