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Allele : Del(9Apoa1-Apoa4)1Hmez deletion, Chr 9, Hafid Mezdour 1

Primary Identifier  MGI:3628802 Allele Type  Targeted
Attribute String  Null/knockout Gene  Del(9Apoa1-Apoa4)1Hmez
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene replaced the coding sequences of apolipoprotein A-I, apolipoprotein C-III and the first two exons of apolipoprotein A-IV. Northern blot of mutant liver and intestine demonstrated successful ablation of expression of all three genes. Western blot confirmed absence of protein of each gene.
  • mutations:
  • Intergenic deletion,
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Apoa1/c3/a4<->,
  • Apoa1/c3/a4<->,
  • Apoa1/Apoc3/Apoa4<tm1Hmez>,
  • Apoa1/Apoc3/Apoa4<tm1Hmez>
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1 Feature

Genome

0 Expresses

3 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories