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Allele : Pdpk1<tm1Maka> 3-phosphoinositide dependent protein kinase 1; targeted mutation 1, Masato Kasuga

Primary Identifier	MGI:3628819	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Pdpk1
Transmission	Germline	Strain of Origin	129S4/SvJae
Is Recombinase	false	Is Wild Type	false

molecularNote

LoxP sites were inserted to flank exons 3 and 4. Transient cre expression removed a floxed neo that was inserted into the locus.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Pdk1<tm1Maka>,
Pdk1<flox>,
Pdk1<tm1Maka>,
betaPdk1<->,
betaPdk1<->,
Pdk1<flox>

earliestPublication:
Hashimoto N, et al. (2006) Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass. Nat Genet 38(5):589-93

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

26 Publication categories

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