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Allele : Xiap<tm1Vdr> X-linked inhibitor of apoptosis; targeted mutation 1, J E Visvader

Primary Identifier  MGI:3629213 Allele Type  Targeted
Attribute String  Null/knockout Gene  Xiap
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace exons 1 and 2 with a neomycin resistance gene. The deleted sequence contains the initiation codon, the first two BIR domains and the third BIR domain. Western blot showed absence of protein in mutants.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Xiap<->,
  • Xiap<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

16 Publication categories

Trail: Allele