|  Help  |  About  |  Contact Us

Allele : Rel<tm1Brv> reticuloendotheliosis oncogene; targeted mutation 1, Rodrigo Bravo

Primary Identifier  MGI:3639342 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rel
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A termination codon was introduced at codon 366 followed by a polyadenylation signal and neomycin selection cassette. This was inserted at the beginning of exon 10 such that exon 10, encoding the transcriptional activation domain, was not expressed. Labelling and immunoprecipitation experiments in mutant splenocytes demonstrated that a stable, truncated form of the encoded protein is expressed from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • c-rel<deltaCT>,
  • c-rel<deltaCT>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories