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Allele : Msn<tm1Sts> moesin; targeted mutation 1, Shoichiro Tsukita

Primary Identifier  MGI:3630284 Allele Type  Targeted
Attribute String  Null/knockout Gene  Msn
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  The 3'end of exon 3 and part of intron 3 was replaced with a loxP-flanked neomycin selection cassette. A splice acceptor (SA) and polyadenylation signal (PA) were also placed at the 3' end of the cassette to minimize the possibility of producing aberrant transcripts that skip exon 3. Immunoblotting assays on mutant male ES cells (-/Y) demonstrated that no full length protein was expressed from this allele.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories