| Primary Identifier | MGI:3639116 | Allele Type | Transgenic |
| Attribute String | Constitutively active, Inserted expressed sequence | Gene | Tg(Myh6-Akt1*T308D*S473D)1Siz |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene contains a constitutively active mouse Akt1, in which critical residues (T308D/S473D) for activation of Akt1 are replaced by negatively charged amino acids, under the control of the mouse alpha-myosin heavy chain. There is about 400 times more transgene product than endogenous Akt1 in cardiac tissue. |
