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Allele : Kmt2a<tm1Djab> lysine (K)-specific methyltransferase 2A; targeted mutation 1, Malek Djabali

Primary Identifier  MGI:3641250 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kmt2a
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The SET domain was replaced with a floxed neomycin resistance gene. A stop codon was introduced in frame to allow termination of protein synthesis in the absence of the SET domain. RT-PCR demonstrated that mutant transcript was expressed at the same levels as wild-type transcripts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • deltaSET,
  • deltaSET,
  • MlldeltaSET-,
  • MlldeltaSET-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories