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Allele : Fxn<tm1Pand> frataxin; targeted mutation 1, Massimo Pandolfo
Primary Identifier  MGI:3641251 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Fxn
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a GAA230 repeat expansion and a floxed neomycin resistance cassette into intron 1 of the locus. Western blot demonstrated that mutants expressed frataxin protein at 75% of wild-type levels in all tissues examined.
  • mutations:
  • Insertion
  • synonyms:
  • frda<230GAA>,
  • frda<230GAA>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

15 Publication categories





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