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Allele : Cast<tm1Tcs> calpastatin; targeted mutation 1, Takaomi C Saido

Primary Identifier  MGI:3641275 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cast
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Most of exon 6 was replaced with a pgk-neo in reverse orientation. Northern and Western blot analysis confirmed recombination of the locus, as did RT-PCR. Calpastatin activity assays indicated that calpastatin activity was reduced to an undetectable level in the mutant mouse brain.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

16 Publication categories