| Primary Identifier | MGI:3640122 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Dp(16Dgcr14-Sept5)3Bld |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A proximal loxP site was targeted into the Es2el gene. The targeting vector replaced a 200-bp fragment containing exon 4. A second loxP site was introduced into the Sept5 gene, replacing exons 2-4. Embryonic stem cells that were double-targeted in trans were subjected to transient Cre expression and underwent recombination to produce a reciprocal duplication of the Es2el-Sept5 interval. |
