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Transgene : Tg(EEF1A1-MCL1)12Jko transgene insertion 12, Keio University School of Medicine, Japan
Primary Identifier  MGI:3640398 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Transgenic mice older than 4 months have hyperplasia of the islets of Langerhans. Tumors, primarily comprising insulin-secreting beta cells, are grossly visible in older mice. Insulin response to fasting glucose challenge is elevated; highest levels are associated with hepatic steatosis. [provided by MGI curators]
  • synonyms:
  • Tg(EEF1A1-MCL1)12Jko,
  • EF1alpha-EAT,
  • Tg(EF1-MCL1)12Jko,
  • transgene insertion 12, Keio University School of Medicine, Japan,
  • Tg(EEF1A1- MCL1)12Jko
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