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Transgene : Tg(Ins2-Cxcl13)1Cys transgene insertion 1, Jason G Cyster
Primary Identifier  MGI:3641324 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Pancreatic islets of transgenic mice are disrupted by lymphocyte infiltrates that form secondary lymphoid-like structures. C57BL/6 transgenic mice maintain normal blood glucose levels and beta cell numbers even at 16 months. The transgene accelerates diabetes onset/progression in NOD mice. [provided by MGI curators]
  • synonyms:
  • transgene insertion 1, Jason G Cyster,
  • RIP-BLC1,
  • Tg(Ins2-Cxcl13)1Cys,
  • RIP-CXCL13
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