Primary Identifier | MGI:3641338 | Allele Type | Targeted |
Attribute String | Humanized sequence, Modified isoform(s) | Gene | Ryr2 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = TVB2. |
molecularNote | A targeting vector was used to introduce an R4496C mutation into exon 94 of the locus. The mutation is the mouse equivalent to the R4497C mutations identified in CPVT families. LoxP sites were inserted to flank the exon. |