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Allele : Ryr2<tm1Sgp> ryanodine receptor 2, cardiac; targeted mutation 1, Silvia G Priori

Primary Identifier  MGI:3641338 Allele Type  Targeted
Attribute String  Humanized sequence, Modified isoform(s) Gene  Ryr2
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = TVB2.
molecularNote  A targeting vector was used to introduce an R4496C mutation into exon 94 of the locus. The mutation is the mouse equivalent to the R4497C mutations identified in CPVT families. LoxP sites were inserted to flank the exon.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Ryr2<R4496C>,
  • Ryr2<R4496C>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories

Trail: Allele