Primary Identifier | MGI:3640383 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Myc |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Mice carrying the Myctm1Dmlo allele were crossed with mice expressing cre recombinase, resulting in the loss of the floxed neo while the human MYC carboxy terminal remained in place of the endogenous sequence and the 3'UTR was replaced by late SV40 3' UTR. |