Primary Identifier | MGI:3652526 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Ighg1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | true | Is Wild Type | false |
molecularNote | An IRES-cre was inserted into the 3' region of the Cgamma1 locus between the last membrane-coding exon and its polyadenylation sites. This targeting design allows for the expression from the locus of a bicistronic mRNA consisting of the Cgamma1 and Cre transcript. An FRT site flanked neomycin resistance gene cassette was removed via Flp recombinase expression. |