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Allele : Dapp1<Gt(OST111213)Lex> dual adaptor for phosphotyrosine and 3-phosphoinositides 1; gene trap OST111213, Lexicon Genetics

Primary Identifier  MGI:3652582 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Dapp1
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
molecularNote  The gene trap vector integrated between the two exons that contribute equally to the complete SH2 domain. A truncation was predicted in the middle of the SH2 domain at amino acid 74, which would result in a nonfunctional SH2 domain. Northern blot and RT-PCR confirmed loss of wild-type transcript in mutants.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Bam32<->,
  • Dapp1<Gt708Lex>,
  • Dapp1<Gt708Lex>,
  • Bam32<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele