Primary Identifier | MGI:1347063 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 26377 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in liver left lobe; liver right lobe; olfactory epithelium; and thymus primordium. Orthologous to human DAPP1 (dual adaptor of phosphotyrosine and 3-phosphoinositides 1). PHENOTYPE: Inactivation of this gene invokes immune defects stemming from impaired B cell receptor crosslinking. [provided by MGI curators] |