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Allele : Zfp423<Gt(XH542)Byg> zinc finger protein 423; gene trap XH542, BayGenomics

Primary Identifier  MGI:3653507 Allele Type  Gene trapped
Attribute String  Hypomorph Gene  Zfp423
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Bay Genomics gene trap vector pGt1Lxf was randomly inserted 11kb downstream of exon 3 in intron 3 which is 75 kb in size. RNA for the wild-type allele was detected in the brain by RT-PCR along with a larger band in mice carrying the gene trap allele and lacking the wild-type allele (J:111316). An independent report indicated that this allele is hypomorphic and that residual low-level expression of a properly spliced transcript is found in homozygous mice (J:114758).
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Zfp423<Gt(pGT1Lxf)5Byg>,
  • Zfp423<Gt(pGT1Lxf)5Byg>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories