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Allele : Kl<tm2Yin> klotho; targeted mutation 2, Yo-ichi Nabeshima

Primary Identifier  MGI:3653671 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Kl
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  false Is Wild Type  false
molecularNote  A 681 bp fragment of exon 1 was replaced with a lacZ-neomycin fusion gene (betageo) and a floxed PGK-neo cassette. The floxed neo was removed by cre mediated recombination. LacZ expression is seen in a pattern similar to expression of the endogenous gene. Western blot analysis confirmed the absence of protein in homozygotes
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • kl<-geo>,
  • kl<-geo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories