Primary Identifier | MGI:3653679 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-CDK5R1/GFP)337Lht |
Strain of Origin | C57BL/6J | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The transgene expresses the carboxy-terminal proteolytic fragment (p25) of human cyclin-dependent kinase 5, regulatory subunit 1, bearing a carboxy-terminal green fluorescent protein (GFP) tag, under control of the tetracycline operator. The purpose of the GFP tag is to differentiate immunologically the transgene-encoded p25 from the endogenous p35 protein. |