Primary Identifier | MGI:3654106 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Xrcc2 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
description | This allele was generated from Xrcc2tm2Pmc. |
molecularNote | A floxed neo cassette was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 (75% of the open reading frame). RT-PCR failed to detect transcript in mutant mouse embryonic fibroblasts. |