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Allele : Tirap<tm1Aki> toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; targeted mutation 1, Shizuo Akira
Primary Identifier  MGI:3654146 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tirap
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace the two exons encoding the TIR domain with a neomycin resistance gene. The insertion created a stop codon in the N-terminal portion of the locus. Immunoblot confirmed that disruption of the locus abolished the expression of protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Mal<->,
  • Tirap-,
  • Mal<->,
  • Tirap-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

39 Publication categories





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