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Allele : Ptch2<tm1Hui> patched 2; targeted mutation 1, Chi-Chung Hui

Primary Identifier  MGI:3656034 Allele Type  Targeted
Attribute String  Hypomorph Gene  Ptch2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 6. Northern blot and RT-PCR analysis indicated that aberrant in-frame splice transcripts lacking exon 6, exons 5 and 6 or exons 6 and 7 are expressed from this allele. Mutant proteins with partial function are predicted to be expressed suggesting that this allele is a hypomorph.
  • mutations:
  • Insertion
  • synonyms:
  • Ptc2<tm1>,
  • Ptc2<tm1>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories