| Primary Identifier | MGI:3663738 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Lrp5 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Lexicon |
| molecularNote | A targeting vector was designed to inactivate the locus by inserting an IRES-betagal-MC1-neo into exon 1. Expression of the betagal would have been under the control of the endogenous promoter, however, no expression was detected. RT-PCR failed to detect wild-type transcripts resulting from exon 1. Protein analysis failed to detect immunoreactivity in mutants. |
