| Primary Identifier | MGI:3663799 | Allele Type | Targeted |
| Attribute String | Constitutively active | Gene | Hck |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector was designed to introduce the tyrosine 499 to phenylalanine substitution (Y499F) and a stop cassette into exon 13. An IRES-neomycin was included in the vector. RT-PCR confirmed the mutated sequence. Western blot detected reduced levels of both isoforms created by the locus. |
