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Allele : Igkc<tm2(IGKC)Cgn> immunoglobulin kappa constant; targeted mutation 2, University of Cologne

Primary Identifier  MGI:3664449 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Igkc
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert the human IGKC and a neo cassette such that the sequence containing a splice signal and 12 base pairs of endogenous sequence were replaced. The remainder of the locus was rendered nonfunctional. Flow cytometry demonstrated the expression of humanized proteins on B cell surfaces.
  • mutations:
  • Insertion
  • synonyms:
  • CkappaR,
  • CkappaR
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories