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Allele : Braf<tm1(ARAF)Urr> Braf transforming gene; targeted mutation 1, Ulf R Rapp

Primary Identifier  MGI:3664469 Allele Type  Targeted
Gene  Braf Transmission  Germline
Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The human ARAF cDNA was introduced in frame with exon 3 of the locus. This exon is common to all three isoforms and harbors the beginning of the Ras binding domain. RT-PCR and Western blot confirmed the production of chimeric transcripts and protein from the locus. A floxed neo included in the vector did not interfere with expression of the protein.
  • mutations:
  • Insertion
  • synonyms:
  • B-RAF<KIN>,
  • B-RAF<KIN>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele